Immunology and Obesity

http://www.nature.com/ni/journal/v13/n8/full/ni.2343.html?WT.ec_id=NI-201208

Article from Nature Immunology discussing the effects of obesity on the immune system. Some facts from the article: Obesity induced inflammation contributes to the development of type 2 diabetes, atherosclerosis, liver disease and some forms of cancer. Diet induced obesity in mice impairs T cell response and causes greater severity of disease and death after infection with influenza. Obesity is associated with aberrant population expansion of cells of the immune system in adipose (fat) tissue. This produces chronic inflammation which can lead to neurodegeneration and type 2 diabetes. Obesity can compromise the efficacy of vaccination against influenza, hepatitis B and tetanus.